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Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул
D.S.
За карткою клієнта «D.S.» нараховуються бонусні бали (крім акційних товарів)
D.S.

Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

код товару: ЦБ000043955
Упаковка / 10 ампул
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Ціна дійсна при резервуванні

Аптеки
від 600.90 грн
Упаковка
1
ампула
0

D.S.
За карткою клієнта «D.S.» нараховуються бонусні бали (крім акційних товарів)
D.S.
Доставка в: Львів >
Особливості застосування
Водіям - з обережністю
Водіям з обережністю
Дорослим - дозволено
Дорослим дозволено
Дітям - заборонено
Дітям заборонено
Вагітним - за призначенням лікаря з урахуванням користь/ризик
Вагітним за призначенням лікаря з урахуванням користь/ризик
Алергікам - з обережністю
Алергікам з обережністю
Годуючим - за призначенням лікаря
Годуючим за призначенням лікаря
Діабетикам - з обережністю
Діабетикам з обережністю
Температура зберігання - не вище 25°C
Температура зберігання не вище 25°C
Взаємодія з їжею - не має значення
Взаємодія з їжею не має значення

Торгівельна назва Бупівакаїн
Форма випуску розчин для ін'єкцій
Виробник Демо Са Фармасьютикал Індастрі
Країна власник ліцензії Греція
Умови відпуску Потрібен рецепт
Вид упаковки ампула
Кількість в упаковці 10 ампула(и)
Дивитися властивості номенклатури Дивитися інструкцію
Доставка в: Львів >
Здоров'я народу
Є в наявності Є в наявності
від 354.20 грн

Загальна характеристика: Загальна характеристика Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

  • Виробник: Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

    <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-bidi-font-weight:bold'>ДЕМО СА ФАРМАСЬЮТІКАЛ ІНДАСТРІ.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-bidi-font-weight:bold'>ТО «НІКО».</span></p>
  • Умови відпуску:

    <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'> </b><span lang='UK' style='mso-ansi-language:UK'>За рецептом.</span></p>
  • Лікарська форма:

    <p><b land='' style=''> </b><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Розчин для ін’єкцій.</span></p> <p><i land='' style=''>Основні фізико-хімічні властивості</i><i land='' style=''>: </i><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-ansi-language:UK;mso-bidi-font-weight: bold;mso-bidi-font-style:italic'>п</span><span style='mso-bidi-font-size: 12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style:italic' style='mso-bidi-font-size: 12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style:italic'>роз</span><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-ansi-language:UK;mso-bidi-font-weight: bold;mso-bidi-font-style:italic'>ора</span><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style: italic'> </span><span style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight: bold;mso-bidi-font-style:italic' style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight: bold;mso-bidi-font-style:italic'>бе</span><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-ansi-language:UK;mso-bidi-font-weight: bold;mso-bidi-font-style:italic'>збарвна</span><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style: italic'> </span><span style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight: bold;mso-bidi-font-style:italic' style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight: bold;mso-bidi-font-style:italic'>р</span><span lang='UK' style='mso-bidi-font-size: 12.0pt;mso-ansi-language:UK;mso-bidi-font-weight:bold;mso-bidi-font-style:italic'>ідина</span><span style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style: italic' style='mso-bidi-font-size:12.0pt;mso-bidi-font-weight:bold;mso-bidi-font-style: italic'>.</span><b land='' style=''></b></p>
  • Упаковка:

    <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'></b><span lang='UK' style='mso-ansi-language:UK'> По 10 мл в ампулах № 10.</span></p> <p><span class='hps' style=''> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>По 10 мл в ампулах № 10</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>.</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'></span></p> <p><span class='hps' style=''>Категория</span><span class='hps' style=''> </span><span class='hps' style=''>отпуска.</span><span class='hps' style=''> </span><span class='hps' style=''>По рецепту.</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'></span></p> <p><span class='hps' style=''>Производител</span><span class='hps' style=''>ь.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>ДЕМО СА ФАРМАСЬЮТИКАЛ ИНДАСТРИ.</span></p> <p><span class='hps' style=''>ООО «</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>НИКО».</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Местонахождение производител</b><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>я</b><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'> и адрес места осуществления </b><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>его</b><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'> деятельности.</b></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>21-й км Национальной Дороги Афины-Ламия, Крионери Аттика, 14568, Греция.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Тел</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'>.: +30 210 8161802</span></p> <p><span lang='EN-US' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:EN-US'>E-mail: </span><span lang='UK' style=''>info@demo.gr</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'></span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Украина, 61068, г. Харьков, ул. Фесенковская, 4А.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Тел</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'>.: +38 (095) 282-66-10</span></p> <p><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: EN-US'>E-mail:</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span lang='UK' style=''>office@nikopharm.com.ua</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'></span></p>
  • Фармацевтична група:

    <p><b land='' style=''> </b><span class='IeoouayiaoeieaHTML1' style=''>Препарати для місцевої анестезії. </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Код АТ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Х</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span class='IeoouayiaoeieaHTML1' style=''>N</span><span class='IeoouayiaoeieaHTML1' style=''>01 01.</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'></span></p>
  • Код АТХ:

Протипоказання: Протипоказання Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

  • <p><span lang='UK' style='font-size:12.0pt
  • font-family: "Times New Roman","serif"
  • mso-fareast-language:RU'>Гіперчутливість до місцевих анестетиків амідного типу або до інших складових препарату. Бупівакаїн не застосовують для внутрішньовенної реґіонарної анестезії (блокада Бієра). Бупівакаїн не застосовують для епідуральної анестезії пацієнтам із вираженою артеріальною гіпотензією, наприклад у випадку кардіогенного або гіповолемічного шоку. </span><span lang='UK' style='font-size:12.0pt
  • font-family:"Times New Roman","serif"
  • mso-fareast-font-family:HiddenHorzOCR
  • mso-fareast-language:EN-US'>Епідуральна анестезія незалежно від місцевого анестетика, що застосовується, має свої протипоказання, які включають: </span></p> <p><span lang='UK' style='font-size: 12.0pt
  • font-family:Symbol
  • mso-fareast-font-family:Symbol
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  • mso-fareast-language:EN-US'>- </span><span lang='UK' style='font-size:12.0pt
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  • mso-fareast-font-family:HiddenHorzOCR
  • mso-fareast-language:EN-US'>захворювання нервової системи в активній стадії: менінгіт, поліомієліт, внутрішньочерепний крововилив, підгостра комбінована дегенерація спинного мозку внаслідок перніціозної анемії та пухлин головного та спинного мозку
  • </span></p> <p><span lang='UK' style='font-size:12.0pt
  • font-family:Symbol
  • mso-fareast-font-family:Symbol
  • mso-bidi-font-family:Symbol
  • mso-fareast-language:EN-US'>- </span><span lang='UK' style='font-size:12.0pt
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  • mso-fareast-font-family:HiddenHorzOCR
  • mso-fareast-language:EN-US'>туберкульоз хребта
  • </span></p> <p><span lang='UK' style='font-size:12.0pt
  • font-family:Symbol
  • mso-fareast-font-family:Symbol
  • mso-bidi-font-family:Symbol
  • mso-fareast-language:EN-US'>- </span><span lang='UK' style='font-size:12.0pt
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  • mso-fareast-font-family:HiddenHorzOCR
  • mso-fareast-language:EN-US'>гнійну інфекцію шкіри у місці або поруч із ділянкою проведення люмбарної пункції
  • </span></p> <p><span lang='UK' style='font-size:12.0pt
  • font-family:Symbol
  • mso-fareast-font-family:Symbol
  • mso-bidi-font-family:Symbol
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  • mso-fareast-font-family:HiddenHorzOCR
  • mso-fareast-language:EN-US'>порушення згортання крові або поточне лікування антикоагулянтами.</span></p>

Застосування: Застосування Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ідповідне реанімаційне обладнання повинно бути завжди доступним при проведенні місцевої або загальної анестезії. ідповідальний лікар повинен вжити необхідних заходів обережності, щоб уникнути внутрішньосудинного введення препарату (див. розділ «Спосіб застосування та дози»). Перш ніж розпочати проведення будь-якої блокадної анестезії, необхідно забезпечити доступ для внутрішньовенного введення лікарських засобів з метою проведення реанімаційних заходів. Лікарі повинні отримати відповідний та достатній рівень підготовки для проведення процедури та повинні бути ознайомлені з діагностикою та лікуванням побічних ефектів, системної токсичності або інших ускладнень (див. розділи «Передозування» і «Побічні реакції»).</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Блокада великих периферичних нервів може потребувати застосування великих об’ємів місцевого анестетика на дуже васкуляризованих ділянках, часто поблизу великих судин, де існує підвищений ризик внутрішньосудинного введення та/або системної абсорбції. Це може призвести до утворення високих концентрацій препарату в плазмі крові.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Передозування або випадкове внутрішньовенне введення препарату може призвести до розвитку токсичних реакцій.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Через повільне накопичення бупівакаїну гідрохлориду введення повторних доз може призвести до значного збільшення рівнів препарату в крові з кожною повторною дозою. Переносимість препарату змінюється разом зі станом пацієнта.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Хоча регіонарна анестезія часто є оптимальним методом проведення анестезії, деякі пацієнти для того, щоб знизити ризик розвитку небезпечних побічних ефектів, потребують особливої уваги:</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пацієнтам літнього віку і пацієнтам із ослабленим загальним станом здоров’я необхідно зменшити дозу препарату співмірно з їх фізичним станом.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пацієнти з частковою або повною блокадою серця – через те, що місцеві анестетики можуть пригнічувати провідність міокарда.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пацієнти з прогресуючим захворюванням печінки або тяжкою нирковою дисфункцією.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пацієнти </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>на</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> пізніх стадіях вагітності.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пацієнти, які приймають антиаритмічні засоби ІІІ класу (наприклад, аміодарон), повинні перебувати під ретельним наглядом персоналу, також повинен проводитися ЕКГ-нагляд, оскільки кардіологічні ефекти препаратів можуть бути адитивними.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Пацієнти з алергічною реакцією на місцеві анестетики ефірного типу (прокаїн, тетракаїн, бензокаїн і т.д.) не продемонстрували перехресної чутливості до препаратів амідного типу, таких як бупівакаїн.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Деякі процедури, пов</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>’</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>язані з місцевою анестезією, можуть призводити до розвитку серйозних небажаних реакцій, незалежно від типу застосованого місцевого анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Місцеві анестетики повинні застосовуватися з обережністю для епідуральної анестезії у пацієнтів із порушеною серцево-судинною функцією, оскільки такі пацієнти мають менше можливостей компенсувати функціональні зміни, пов’язані з подовженням атріовентрикулярної провідності, що була викликана дією цих лікарських засобів.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Фізіологічні ефекти, що розвиваються у результаті проведення центральної невральної блокади, більш виражені при наявності артеріальної гіпотензії. Під час проведення епідуральної анестезії у пацієнтів з гіповолемією з будь-якої причини може розвинутися раптова і тяжка артеріальна гіпотензія. Тому у пацієнтів з нелікованою гіповолемією або значним порушенням венозного відтоку слід уникати проведення епідуральної анестезії або застосовувати її з обережністю.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- У дуже рідких випадках ретробульбарні ін’єкції можуть досягати черепного субарахноїдального простору та спричиняти появу тимчасової сліпоти, серцево-судинної недостатності, апное та судом.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Ретро- та навколобульбарні ін’єкції місцевих анестетиків можуть становити певний ризик для розвитку стійкої дисфункції очних м’язів. Основними причинами є травматичне ураження нервів та/або місцеві токсичні ефекти введеного місцевого анестетика на м’язи та нерви. Тяжкість таких тканинних реакцій залежить від ступеня травми, концентрації місцевого анестетика і тривалості впливу місцевого анестетика на тканини. З цієї причини, як і у випадку з усіма місцевими анестетиками, слід застосовувати найнижчу ефективну концентрацію та дозу місцевого анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Судинозвужувальні лікарські засоби можуть посилювати реакції тканин, тому повинні застосовуватися тільки тоді, коли це показано.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- ипадкове внутрішньоартеріальне введення низьких доз місцевих анестетиків у ділянку голови та шиї, включаючи ретробульбарні, стоматологічні блокади та блокаду зірчастого вузла, може призвести до розвитку системної токсичності.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Парацервікальна блокада може чинити більший негативний вплив на плід, ніж інші види застосовуваної в акушерстві блокадної анестезії. Через системну токсичність бупівакаїну слід бути особливо обережними при застосуванні бупівакаїну для парацервікальної блокади.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Зафіксовано випадки хондролізу у пацієнтів, які у післяопераційний період отримували внутрішньосуглобові тривалі інфузії місцевих анестетиків. У більшості випадків повідомлялося про розвиток хондролізу із залученням плечового суглоба.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Через наявність певної кількості сприяючих причин і суперечливих наукових даних про механізм дії причинно-наслідковий зв’язок не був встановлений. Тривала внутрішньосуглобова інфузія не є затвердженим показанням для застосування препарату.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Проведення епідуральної анестезії будь-яким місцевим анестетиком може призвести до розвитку артеріальної гіпотензії та брадикардії, появу яких слід передбачати та проводити відповідні запобіжні заходи, що можуть включати попереднє введення у систему кровообігу кристалоїдного або колоїдного розчину. У випадку розвитку артеріальної гіпотензії слід внутрішньовенно ввести судинозвужувальний препарат, такий як ефедрин, у дозі 10-15 мг. Тяжка артеріальна гіпотензія може виникнути в результаті гіповолемії внаслідок кровотечі або зневоднення, або аорто-порожнистої оклюзії у пацієнтів із масивним асцитом, великими пухлинами черевної порожнини або на пізніх термінах вагітності. Значної артеріальної гіпотензії слід уникати у пацієнтів із серцевою декомпенсацією.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Під час проведення епідуральної анестезії у пацієнтів з гіповолемією з будь-якої причини може розвинутися раптова і тяжка артеріальна гіпотензія.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Епідуральна анестезія може викликати параліч міжреберних м’язів, а пацієнти з плевральним випотом можуть страждати від дихальної недостатності. Сепсис може збільшити ризик утворення інтраспінального абсцесу в післяопераційному періоді.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>При введенні бупівакаїну шляхом внутрішньосуглобової ін’єкції рекомендується бути обережними у випадку підозри на нещодавню обширну внутрішньосуглобову травму або за наявності обширних відкритих поверхонь у суглобі, утворених під час хірургічних процедур, оскільки це може прискорити абсорбцію та призвести до появи підвищених концентрацій препарату в плазмі крові.</span></p> <p><i style='mso-bidi-font-style: normal' style='mso-bidi-font-style: normal'>Дозування</i></p> <p><i style='mso-bidi-font-style: normal' style='mso-bidi-font-style: normal'>Дорослі</i></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Таблиця 1 являє собою керівництво щодо дозування препарату у дорослих середнього віку при застосуванні найбільш часто використовуваних методик проведення блокади. Цифри відображають очікуваний діапазон середніх допустимих доз препарату. Стандартні навчальні посібники повинні бути враховані у випадку наявності факторів, що впливають на окремо взяті методики проведення блокади, та для забезпечення індивідуальних вимог пацієнтів.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Зверніть увагу! У разі проведення тривалих блокад або шляхом безперервної інфузії, або шляхом повторного болюсного введення слід враховувати ризик досягнення токсичної концентрації препарату в плазмі крові або ризик місцевого пошкодження нервів.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Досвід лікарів і дані про фізичний стан пацієнта є важливими факторами при розрахунку необхідної дози препарату. Слід застосовувати найнижчі, необхідні для проведення адекватної анестезії, дози препарату. На початку та під час проведення анестезії зафіксовано випадки індивідуальної мінливості.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Таблиця 1</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Рекомендації щодо дозування препарату у дорослих</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Концентрація,</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>мг/мл</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Об’єм,</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>мл</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Доза,</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>мг</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Початок дії, хв</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Тривалість ефекту, години</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>АНЕСТЕЗІЯ ПРИ ХІРУРГІЧНИХ ТРУЧАННЯХ</b></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Люмбальне епідуральне введення препарату1)</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Хірургічне втручання</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>75-150</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>2-3</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Люмбальне епідуральне введення препарату1)</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Кесарів розтин</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>75-150</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>2-3</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Торакальне епідуральне введення препарату1)</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Хірургічне втручання</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5-10</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>25-50</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>10-15</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>2-3</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Каудальна епідуральна блокада1)</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>20-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>100-150</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>2-3</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Блокада великих нервів2)</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>(наприклад, плечового сплетіння, стегнового, сідничного нервів)</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>10-35</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>50-175</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>15-30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>4-8</span></p> <p><b style='mso-bidi-font-weight: normal' style='mso-bidi-font-weight: normal'>Місцева анестезія</b></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>(наприклад, блокади та інфільтрація невеликих нервів)</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>5</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>? 30</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>?150</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>1-10</span></p> <p><span lang='UK' style='font-size: 12.0pt;line-height:90%;font-family:"Times New Roman","serif";mso-fareast-language: RU'>3-8</span></p> <p><sup land='' style=''>1)</sup><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> Доза включає в себе досліджувану дозу.</span></p>

Протипоказання: Протипоказання Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

  • <p><span lang='UK' style='font-size:12.0pt
  • font-family:"Times New Roman","serif"
  • mso-fareast-language:RU'>Бупівакаїн застосовується для проведення місцевої анестезії шляхом черезшкірної інфільтрації, периферичної(-их) нервової(-их) блокади(блокад) і центральної невральної блокади (каудальної або епідуральної), тобто застосовується фахівцем у тих ситуаціях, коли вимагається проведення тривалої анестезії. Оскільки сенсорна нервова блокада більш виражена, ніж моторна блокада, Бупівакаїн особливо ефективний для полегшення болю, наприклад під час пологів.</span></p>

Побічна дія: Побічна дія Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Ознаки розвитку токсичного впливу на центральну нервову систему (ЦНС) (див. розділ. «Побічні реакції») зазвичай передують серцево-судинним ефектам, оскільки ознаки токсичного впливу на ЦНС спостерігаються при більш низьких концентраціях препарату в плазмі крові. Прямі серцеві ефекти місцевих анестетиків включають сповільнену провідність, негативний інотропізм та, зрештою, зупинку серця.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Непрямі серцево-судинні ефекти (артеріальна гіпотензія, брадикардія) можуть розвинутися після епідуральної блокади, залежно від ступеня супутньої симпатичної блокади.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Фармакокінетика. </i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>еличина рКа бупівакаїну становить 8,2, а коефіцієнт розподілу дорівнює 346 (25 °C n-октанол/фосфатний буфер при pH 7,4). Метаболіти володіють фармакологічною активністю, але меншою, ніж у бупівакаїну.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Концентрація бупівакаїну в плазмі крові залежить від дози, шляху введення та васкуляризації місця ін’єкції.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Бупівакаїн демонструє повну та двофазну абсорбцію з епідурального простору із періодами напіввиведення приблизно 7 хвилин та 6 годин відповідно. Повільна абсорбція є фактором, що обмежує швидкість виведення бупівакаїну та пояснює, чому очевидний термінальний період напіввиведення після епідурального застосування більший, ніж після внутрішньовенного введення.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Загальний плазмовий кліренс бупівакаїну становить 0,58 л/хв, об’єм розподілу в рівноважному стані – 73 л, термінальний період напіввиведення – 2,7 години і проміжний коефіцієнт печінкової екстракції – 0,38 після внутрішньовенного введення препарату. Бупівакаїн зв’язується у плазмі крові переважно з альфа-1-кислим глікопротеїном, зв’язана фракція становить 96 %. Кліренс бупівакаїну майже повністю залежить від метаболізму печінки і більш чутливий до змін, що стосуються активності власних печінкових ферментів, ніж до печінкової перфузії.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Педіатрична популяція</i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>У дітей фармакокінетика препарату подібна до фармакокінетики у дорослих.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Збільшення загальної концентрації препарату в плазмі крові було зафіксовано під час проведення тривалої епідуральної інфузії. Це пов’язано з післяопераційним підвищенням рівнів альфа-1-кислого глікопротеїну. Концентрація незв’язаного препарату, тобто фармакологічно активного, схожа до і після операції.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Бупівакаїн легко проходить через плаценту і швидко досягає рівноважного стану щодо концентрації незв’язаного препарату. Ступінь зв’язування з білками плазми крові у плода менше, ніж у матері, що призводить до зниження загальних концентрацій препарату в плазмі крові у плода.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Бупівакаїн широко метаболізується в печінці, переважно шляхом ароматичного гідроксилювання до 4-гідроксибупівакаїну та N-деалкілування до РРХ, причому обидва ці шляхи опосередковуються цитохромом Р450 3А4. Близько 1 % бупівакаїну впродовж 24 годин виводиться із сечею у вигляді незміненого препарату і приблизно 5 % – у вигляді PPX. Концентрації PPX і 4-гідроксибупівакаїну в плазмі крові під час і після тривалого введення бупівакаїну залишаються низькими порівняно з концентрацією вихідного лікарського засобу.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Для того, щоб уникнути внутрішньосудинної ін’єкції, аспіраційну пробу рекомендується провести перед та повторити під час введення загальної дози препарату, яку слід вводити повільно або окремими дозами, зі швидкістю 25-50 мг/хв, одночасно уважно спостерігаючи за життєво важливими функціями пацієнта і підтримуючи з ним вербальний контакт. ипадкову внутрішньосудинну ін</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>’</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>єкцію можна визначити за тимчасовим підвищенням частоти серцевих скорочень, а випадкову інтратекальну ін</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>’</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>єкцію – за ознаками спінального блоку. При виникненні симптомів інтоксикації введення препарату слід негайно припинити (див. розділ «Побічні реакції»). У разі використання бупівакаїну із застосуванням будь-яких інших технік для одного й того ж пацієнта дозування не повинно перевищувати 150 мг.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Накопичений дотепер досвід показує, що доза препарату 400 мг, яку вводять протягом 24 годин, дорослою людиною середнього віку переноситься добре.</span></p> <p><i land='' style=''>Порядок роботи з ампулою</i></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>1. ідокремити одну ампулу від блоку і струснути її, утримуючи за горлечко (Рис. 1). </span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>2. Стиснути ампулу рукою (при цьому не повинно відбуватися виділення препарату) і обертальними рухами звернути і відокремити голівку (Рис. 2). </span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>3. Через отвір, що утворився, негайно з’єднати шприц з ампулою (Рис. 3). </span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>4. Перевернути ампулу і повільно втягнути у шприц її вміст (Рис. 4).</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>5. Надіти голку на шприц.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> Рис. 1 Рис. 2 Рис. 3 Рис. 4</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-fareast-language:RU;mso-bidi-font-style:italic'>ипадкові внутрішньосудинні ін’єкції місцевих анестетиків можуть спричинити негайні (від кількох секунд до кількох хвилин) системні токсичні реакції. У випадку передозування системна токсичність проявляється пізніше (через 15–60 хвилин після ін’єкції) через повільніше збільшення концентрації місцевого анестетика у крові (див. розділ «Побічні реакції»).</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>ипадкове введення препарату в субарахноїдальний простір може призвести до розвитку дуже високого ступеня спінальної анестезії, можливо, з апное і тяжкою артеріальною гіпотензією.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Профіль небажаних реакцій препарату Бупівакаїн подібний до профілю небажаних реакцій, що виникають при застосуванні інших місцевих анестетиків тривалої дії. Небажані реакції, спричинені самим препаратом, важко відрізнити від фізіологічних ефектів блокади нервових волокон (наприклад, зниження артеріального тиску, брадикардія), а також явищ, спричинених безпосередньо (наприклад, травми нервів) або опосередковано (наприклад, епідуральний абсцес) голковою пункцією.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Неврологічні ушкодження є рідкісними, але добре відомими наслідками регіональної, особливо епідуральної та спінальної, анестезії. они можуть бути пов’язані з декількома причинами, наприклад прямою травмою спинного мозку або спинномозкових нервів, синдромом ураження передньої спинномозкової артерії, ін’єкцією подразнюючої речовини або ін’єкцією нестерильного розчину. Це може призвести до парестезії або анестезії в локалізованих ділянках, моторної слабкості, втрати контролю над сфінктером і параплегії. Іноді ці явища є довготривалими.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Небажані реакції перераховані нижче за класами систем органів тіла і абсолютною частотою. Частота визначається як дуже часто (? 1/10), часто (від ? 1/100 до < 1/10), нечасто (від ? 1/1000 до < 1/100), рідко (від ? 1/10000 до < 1/1000), частота невідома</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>(</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>не може бути оцінена за наявними даними).</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Таблиця 2</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Небажані реакції, що виникають при застосуванні препарата</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Клас систем органів</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Класифікація за частотою</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Небажана реакція на застосування препарату</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>З боку імунної системи</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>рідко</span></p>

Застосування в період вагітності: Застосування в період вагітності Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:HiddenHorzOCR;mso-fareast-language:EN-US'>Доказів несприятливого впливу на перебіг вагітності у людини немає, але бупівакаїн не слід застосовувати на ранніх стадіях вагітності, крім випадків, коли вважається, що користь переважатиме ризик.</span></p>

Діти: Діти Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>За такими показаннями бупівакаїн не застосовують дітям.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>При таких показаниях бупивакаин не применяют детям.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Передозировка.</b></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>Случайные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>внут</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>рисосудистые инъекции </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-fareast-language:RU;mso-bidi-font-style:italic'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>в мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>ут </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic'>вызвать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-fareast-language:RU;mso-bidi-font-style:italic'>не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>медленные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>(</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>от нескольких </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>секунд до </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic'>нескольких минут</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";color:windowtext;mso-fareast-language: RU;mso-bidi-font-style:italic'>) системн</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>ые</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'> токсич</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language:RU; mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt; font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language:RU; mso-fareast-language:RU;mso-bidi-font-style:italic'>еские </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'> случае </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-fareast-language:RU;mso-bidi-font-style:italic'>передоз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>ировки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>системна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'> токсичн</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>сть проявля</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size: 12.0pt;font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language: RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>тся поз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style: italic'>же </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";color:windowtext;mso-fareast-language:RU;mso-bidi-font-style: italic'>(через 15–60 </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>минут </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>е инъекции</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-fareast-language:RU;mso-bidi-font-style:italic'>) </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>из-за медленного увеличения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'> м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt;font-family:"Times New Roman","serif";color:windowtext; mso-ansi-language:RU;mso-fareast-language:RU;mso-bidi-font-style:italic'>тного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'>анестетика в кров</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language:RU; mso-fareast-language:RU;mso-bidi-font-style:italic' style='font-size:12.0pt; font-family:"Times New Roman","serif";color:windowtext;mso-ansi-language:RU; mso-fareast-language:RU;mso-bidi-font-style:italic'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; color:windowtext;mso-fareast-language:RU;mso-bidi-font-style:italic'> (см. раздел «Побочные реакции»).</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Побочные реакции.</b><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Случайное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> в субарахно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>дальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ое п</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>ростр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>анство </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>може</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>к</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ию очень </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>соко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>сте</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>пе</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>ни сп</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>нально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'>, во</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>зможно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> апно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>э</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> тяж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>елой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>ально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ией</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Профиль не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>желательных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>й препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> Буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>вака</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>н под</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>профилю не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>желательных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>й, в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>озникающих </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>при </span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>применении других </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>длительного действия</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>. Нежелательные реакции, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>вызванные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>самим препаратом, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>сложно отличить от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ф</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>з</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>олог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еских эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>в блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>волокон (напри</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>мер</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нижен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>артер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ального </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>давления</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>я), а такж</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> яв</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>лений</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>вызванных непосредственно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>(напри</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>мер</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, травм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>в) </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>или </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>опосредова</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>н</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>но (например, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>дуральн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>й абсцес</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>) </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>голо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>чной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>пункц</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ией</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Неврологич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еские повреждения являются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>дкими, </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>но хорошо известными последствиями </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>рег</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>онально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>, особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>енно э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>п</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>дурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> сп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й,</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'>. Они могут быть связаны с </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>несколькими </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>причинами, напри</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>мер</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> прямо</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> травмо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> спинного моз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>га</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>или</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> спинномозговых нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в, синдромом </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>поражения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>передн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ей </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>спинномоз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>говой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>инъекцией раздражающего вещества или инъекцией </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>нестерильного р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>аствора</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>. </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>Это </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>т</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>к</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> парестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>или </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> в локал</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>зован</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ных участках</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, моторной слабост</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>потере </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>контрол</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>я</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> над сф</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>нктером и параплег</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>И</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>но</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>эти</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> яв</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ления являются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>до</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>лговременными.</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>Не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>желательные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> пере</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>числены </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>ниже </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>по</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'> клас</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ам</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>систем орган</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в т</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ла </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> абсолютно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> частот</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>. Частот</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>определяется как</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>очень </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>часто (? 1/10), часто (</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>от</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'> ? 1/100 до < 1/10), нечасто (</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>от</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> ? 1/1000 до < 1/100), р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>дко (</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>от</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> ? 1/10000 до < 1/1000),</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'> частота неизвестна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>(</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>не може</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> б</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ыть </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>оц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нена </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>по</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>имеющимся </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>дан</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ным)</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>Таблица 2</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>е</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>желательные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>и, в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>озникающие при применении </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Клас</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> систем орган</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Клас</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ификац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>по</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> частот</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>е</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>желательная р</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>еакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>применение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>о стороны им</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>мунно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'> систем</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>редко</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Ал</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>ерг</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ч</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>еские </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>реакц</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'>, анаф</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>лактич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еская </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я/шок </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>(</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>. р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>зд</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>л «Особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>»)</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>о стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>нерв</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ной </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>систем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Парестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>головокружение</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>нечасто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Признаки и симптомы токсичности ЦНС (судороги, околоротовая парестезия, онемен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ие я</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>з</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>ка, г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>перакуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>нарушение зрения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>потеря сознания</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, тремор, легк</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>е </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>головокружение</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, шум в у</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>шах</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, дизартр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я, судорожн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ые</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>движения мышц</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>)</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>редко</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Нейропат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>повреждение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>периферич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еских н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ерв</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в, арахно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>дит, парез </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> параплег</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>о стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>орган</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в зр</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ения</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>редко</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Диплопия</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>о стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>сер</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>ц</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>а</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я (см. р</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>зд</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>л «Особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>»)</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>дко</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Остановка </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>сер</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>дца (см</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>. р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>л «Особ</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>»), сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>дечные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>аритм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'></span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Со стороны сосудов</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>очень </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Артер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>альна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>я</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>потенз</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>я (</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'>. р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>е</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>л «Особ</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>»)</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Артер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>альна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>я</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>пертенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>я (</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>. р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>зд</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>л «Особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>»)</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>о стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>хательной систем</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, орган</span><u land='' style=''>о</u><u land='' style=''>в грудно</u><u land='' style=''>й</u><u land='' style=''> кл</u><u land='' style=''>е</u><u land='' style=''>тки </u><u land='' style=''>и</u><u land='' style=''> средост</u><u land='' style=''>е</u><u land='' style=''>н</u><u land='' style=''>и</u><u land='' style=''>я</u><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>редко</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Угнетение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>д</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>хан</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>я</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Со стороны </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>пищеварительной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>систем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>очень часто</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Тошнота</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>Рвота</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>Со стороны </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>почек и мочевыделительной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>систем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>часто</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>За</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>держка мочи</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>После повторных инъекций или длительных инфузий бупивакаина были зарегистрированы случаи печеночной дисфункции с оборотным </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>повышением уровней </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>аспартатам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нотрансфераз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы,</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> алан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>нотрансфераз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>щелочной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>фосфатаз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>руб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>Если во время </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ечения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>буп</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>ном наблюдаются признаки печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еночной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>дисфункц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>применение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> след</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>ует</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> пр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>екратить</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>.</span></p> <p><span class='hps' style=''>Срок годности</span><span class='hps' style=''>. </span><span class='hps' style=''>2</span><span class='hps' style=''>,5</span><span class='hps' style=''> года</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>.</span></p> <p><span class='hps' style=''>Условия</span><span class='hps' style=''> </span><span class='hps' style=''>хранения.</span><span class='hps' style=''> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Хранить в оригинальной упаковке при температуре не выше 25 ?С. Не замораживать. Хранить в недоступном для детей месте. </span></p> <p><span class='hps' style=''>Несовместимость.</span><span class='hps' style=''></span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Алкализация может вызвать осадок, поскольку бупивакаин мало растворим при рН выше 6,5.</span></p>

Умови зберігання: Умови зберігання Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'> </b><a name='StorageConditions' style=''>Зберігати в оригінальній</a><span style='mso-bookmark:StorageConditions' style='mso-bookmark:StorageConditions'> упаковці при температурі не вище 25 ?С. Не заморожувати.</span><span style='mso-bookmark:StorageConditions' style='mso-bookmark:StorageConditions'> Зберігати </span><span style='mso-bookmark:StorageConditions' style='mso-bookmark:StorageConditions'>у недоступному для дітей місці.</span><text land='' style=''> </text></p> <p><b land='' style=''>Несумісність.</b></p> <p><span lang='UK' style='mso-bidi-font-size:12.0pt;mso-ansi-language:UK'>Алкалізація може спричинити осад, оскільки бупівакаїн мало розчинний при рН вище 6,5.</span><span style='mso-bidi-font-size:12.0pt' style='mso-bidi-font-size:12.0pt'></span></p>

Діюча речовина: Діюча речовина Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span style='mso-bookmark:ActiveIngredient' style='mso-bookmark:ActiveIngredient'>діюча речовина: </span><span style='mso-bookmark:ActiveIngredient' style='mso-bookmark:ActiveIngredient'>бупівакаїну гідрохлорид;</span></p> <p><span style='mso-bookmark:ActiveIngredient' style='mso-bookmark:ActiveIngredient'>1 мл розчину містить бупівакаїну гідрохлориду 5 мг;</span></p> <p><span style='mso-bookmark:ActiveIngredient' style='mso-bookmark:ActiveIngredient'>допоміжні речовини:</span><span style='mso-bookmark:ActiveIngredient' style='mso-bookmark:ActiveIngredient'> натрію хлорид, кислота хлористоводнева розведена або натрію гідроксид, вода для ін’єкцій.</span></p>

Водіння авто: Водіння авто Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Бупівакаїн має мінімальний вплив на здатність керувати транспортними засобами та працювати з механізмами. Крім прямого впливу анестетиків місцеві анестетики можуть чинити дуже незначний ефект на психічні функції та координацію рухів навіть у відсутності явного токсичного впливу на ЦНС, а також можуть призводити до тимчасового погіршення рухової активності та уважності.</span></p>

Фармакологічні властивості: Фармакологічні властивості Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Фармакодинаміка. </i></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Бупівакаїну гідрохлорид – місцевий анестетик тривалої дії амідного типу з анестезуючим і аналгетичним ефектом. При застосуванні високих доз досягається хірургічна анестезія, тоді як нижчі дози призводять до сенсорної блокади (аналгезії), що супроводжується менш вираженою моторною блокадою.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Початок і тривалість локального знеболювального ефекту бупівакаїну залежить від дози і місця введення препарату.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Бупівакаїн, як і інші місцеві анестетики, оборотним чином блокує проведення імпульсів у нервових волокнах шляхом пригнічення транспорту іонів натрію через клітинні мембрани нервових волокон. Натрієві канали у нервових мембранах містять рецептори для фіксації молекул місцевого анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Місцеві анестетики можуть чинити подібну дію на інші збудливі мембрани, наприклад у головному мозку і міокарді. У разі, коли надмірна кількість препарату досягає системного кровотоку, можуть з</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>’</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>явитися симптоми і ознаки токсичності, які походять із центральної нервової та серцево-судинної систем.</span></p>

Адреса: Адреса Бупівакаїн розчин для ін'єкцій 5 мг/мл 10 мл 10 ампул

<p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>21-й км Національної Дороги Афіни-Ламія, Кріонері Аттика, 14568, Греція.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Тел</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'>.: +30 210 8161802</span></p> <p><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: EN-US'>E-mail: </span><span lang='UK' style=''>info@demo.gr</span><span lang='EN-US' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:EN-US'></span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Україна, 61068, м. Харків, вул. Фесенківська, 4А.</span></p> <p><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>Тел.: +38 (095) 282-66-10</span><span lang='EN-US' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:EN-US'></span></p> <p><span lang='EN-US' style='mso-fareast-font-family:Calibri;mso-ansi-language: EN-US'>E-mail: </span><a href='mailto:office@nikopharm.com.ua' style=''>office@nikopharm.com.ua</a><span class='MsoHyperlink' style=''></span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>ИНСТРУКЦИЯ</b></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>по медицинскому применению лекарственного средства</b></p> <p><b land='' style=''>Б</b><b land='' style=''>УПИАКАИН</b></p> <p><b land='' style=''>(</b><b land='' style=''>BUPIVA</b><b land='' style=''>С</b><b land='' style=''>AIN</b><b land='' style=''>Е</b><b land='' style=''>)</b></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Состав:</b></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>действующее вещество</i><i land='' style=''>: </i><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:"Arial Unicode MS";mso-fareast-language:RU'>бупивакаина </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:"Arial Unicode MS";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:"Arial Unicode MS";mso-ansi-language:RU;mso-fareast-language: RU'>гидрохлорид</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-font-family:"Arial Unicode MS";mso-fareast-language:RU'>;</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-no-proof: yes'>1 мл </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>раствора содержит бупивакаина гидрохлорида 5 </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-no-proof:yes'>мг;</span></p> <p><i style='mso-bidi-font-style: normal' style='mso-bidi-font-style: normal'>вспомогательные вещества: </i><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>натр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ия</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> хлорид, кислота хлористов</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>одородная разбавленная или </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-fareast-language:RU'>натр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ия</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>дроксид, вода для </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>инъекций</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Лекарственная форма.</b><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'> Раствор для инъекций.</span></p> <p><span class='hps' style=''>Основные</span><span class='hps' style=''> </span><span class='hps' style=''>физико</span><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>-химические</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> </i><span class='hps' style=''>свойства:</span><span class='hps' style=''> </span><span class='hps' style=''>п</span><span class='hps' style=''>розрачн</span><span class='hps' style=''>ая бесцветная жидкость.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Фармакотерапевтическая группа. </b><text land='' style=''>Препараты для местной анестезии. Код АТХ </text><span class='IeoouayiaoeieaHTML1' style=''>N</span><span class='IeoouayiaoeieaHTML1' style=''>01 01.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Фармакологические свойства.</b></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Фармакодинамика. </i></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Буп</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дрохлорид – м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>естный </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> длительного действия </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного тип</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ирующим и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>аналгетич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еским эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фектом. При применении высоких доз дос</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тигается </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рург</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еская </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я, то</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>как более </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ни</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>зкие </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> приводят</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> сенсорно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> (аналгез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>), </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>что </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>провож</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дается </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ее вы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ражен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> моторной блокадо</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Начало и длительность </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>локального </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>обезболивающего эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>висит от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>еста </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Бупивакаин, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>как и другие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тные </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетики, обр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>атимым образом </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>блок</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ирует </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>мпульс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в в нервных </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>в</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>олокнах </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>путем угнетения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>транспорт</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>он</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в натр</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ия</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> через кл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еточные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мембран</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>волокон. Натр</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> канал</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в нерв</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мембранах </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>содержат </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рецепторы для ф</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ксац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> молекул м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>стного анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>М</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>естные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетики мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гут оказывать п</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>од</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>бно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> действие на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>другие возбудимые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мембран</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, напри</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>мер</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в головном моз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ге и </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>окард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> случае</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гда</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif"' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>чрезмерное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>оличество </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> дос</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тигает </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>системного кровоток</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> поя</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ся симптом</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>признаки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>которые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>роисходят из </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>центрально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ной и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дечно</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>-сосудистой систем.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Признаки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ия </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еского </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вли</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>яния </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>на центральну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ную </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>систему</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> (ЦНС)</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> (</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л. «Поб</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>чн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>»)</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'> обычно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пред</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>шествуют </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сердечно-</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>со</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>суди</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>стым эфф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ектам, поскольку </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>признаки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еского </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>лияния </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ЦНС наблюдаются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>при б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>олее н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>изких концентрациях препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Прямые сердечные эффекты мес</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тных </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в включают </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>замедленную </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пров</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имость</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, негативн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нотропизм и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>,</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>наконец, остановку </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>Непрямые сердечно-сосудистые эффекты (артериальная гипотензия, брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я) мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зви</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ть</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>ся п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>пидурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>в зависимости от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пени с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>опутствующей </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>симпатич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еской </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>блокад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Фармакокинетика. </i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>еличина рКа бупивака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>оставляет </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>8,2, а коэффиц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нт р</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>аспределения равен </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>346 (25 °C n-октанол/фосфатный буфер при pH 7,4). Метабол</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>обладают ф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>армаколог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еской </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>активн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ю</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>, но мень</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ше</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>чем </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>у буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Концентрация бупивака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>висит от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>пути </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> васкуляризац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> м</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>та инъекции</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н демонстр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ирует </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>по</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> и двухфазну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> абсорбц</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ю </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>з </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дурального прост</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ранства с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> пер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>одами </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>полувыведения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>приблиз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ительн</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о 7 </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>минут и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>6 </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>часов</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif"' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>соответственно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Медленная абсорбция </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>является </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фактором, о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>граничивающим скорость </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>веден</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>объясняет</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>по</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>ч</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>му очевидн</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й терминальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й пер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>од </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>полувыведения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> эп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дурального </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>применения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>больш</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е,</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>чем </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> внутр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>венного введен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Общий плазменный клиренс бупивакаина составляет 0,58 л/мин, об</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ъем распределения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>авновесном </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>остоянии </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>– 73 л, терм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й пер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>од </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>полувыведения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>– 2,7 </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>часа и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пром</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>уточный </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>эф</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>фиц</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нт печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>еночной э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кстракц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> – 0,38 п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> внутр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>венного введен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>связывается </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> пре</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>имущественно с </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>альфа-1-кисл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м гл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>копроте</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ном</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>,</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>связанная </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фракц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>оставляет </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>96 %. Клиренс бупивакаина почти полностью за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>висит от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>метабол</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ени и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ее </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>чу</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>вствителен к изменениям</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>касающимся </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>активност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>собственных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очных </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>фермент</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>чем к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>но</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>чной </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>перфуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Педиатрич</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>еская </i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>популяция</i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>У д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>тей фармакок</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нетика препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> под</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>бна фармакокинетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> у </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>вз</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>росл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Увеличение общей </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ло </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>зафиксировано во время </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я длительной </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>эпи</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дуральной </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нфуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>Это свя</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>зано </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>операц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионным </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>овышением уровней </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>альфа-1-кислого гл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>копроте</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>связанного препарата</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, то</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> есть </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фармаколог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ески</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> активного</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>,</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> схо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>дна </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>до </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> операц</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н легко про</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>никает </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>через плаценту </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>быстро </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дос</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тигает </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внов</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>есного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>остояния относительно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> не</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вязан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ого препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нь </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вяз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ван</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> б</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>лками плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> у плода мен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ше, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>чем </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>у матер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>чт</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>о приводит к </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нижению </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>общих </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в плазме кров</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> у плода.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Бупивакаин широко метаболизируется в печен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, пре</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>имущественно путем </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ароматич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еского </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дроксил</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ирования </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>до 4-гидроксибуп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> N-деалк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ирования </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>до РРХ, прич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>оба </span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>эти</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>пути являются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>опосредов</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>анными </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>цитохромом Р450 3А4. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Около </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>1 % буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> течение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>24 </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>часов </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вод</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>тся </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с мочой в </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вид</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>зм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ого препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> приблиз</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>итель</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>но 5 % – </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>в</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> вид</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> PPX. Концентрации PPX и 4-гидроксибупивакаина в плазме кров</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>во время и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>длительного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>остаются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>низкими </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>в сравнении с </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>и</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенного средства</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Клинические характеристики.</b></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Показания.</b><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>Буп</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>н </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>применяется </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>для проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>я мес</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>тной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>путем </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>чре</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>скожной и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>нф</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>льтрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>, периферич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>еской</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>(-их) нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ной</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>(-</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>х) блокад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>(блокад) </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> центрально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> неврально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> (каудально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>й</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>или э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>дуральной), то</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'> есть</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'> применяется </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>специалистом </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>в т</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>х ситуац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>ях, ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>гда</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>требуется </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ие длительной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'>Поскольку </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>сенсорна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>я</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'> нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>ная </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>блокада</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU;mso-fareast-language:RU'> </span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>более </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>ражен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>чем моторная </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-fareast-language: RU'>блокада, Буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>н особ</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language:RU'>енно эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>фектив</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>ен для облегчения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>бол</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU;mso-fareast-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-fareast-language:RU'>, напри</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>мер</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-fareast-language:RU'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU;mso-fareast-language:RU'>во время родов</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-fareast-language:RU'>.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Противопоказания. </b></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Гиперчувствительность к местным анестетикам амидного типа или к другим составляющим препарата.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Бупивакаин не применяют для внутривенной регионарной анестезии (блокада Биера). Бупивакаин не применяют для эпидуральной анестезии пациентам с выраженной артериальной гипотензией, например в случае кардиогенного или гиповолемического шока. Эпидуральная анестезия независимо от местного анестетика, который применяется, имеет свои противопоказания, которые включают:</span></p> <p><span style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU' style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>заболевания нервной системы в активной стадии: менингит, полиомиелит, внутричерепное кровоизлияние, подострая комбинированная дегенерация спинного мозга вследствие пернициозной анемии и опухолей головного и спинного мозга; </span></p> <p><span style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU' style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>туберкулез позвоночника; </span></p> <p><span style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU' style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>гнойную инфекцию кожи в месте или рядом с участком проведения люмбарной пункции;</span></p> <p><span style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU' style='font-size:12.0pt;font-family:Symbol;mso-fareast-font-family:Symbol; mso-bidi-font-family:Symbol;mso-ansi-language:RU'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>нарушение свертывания крови или текущее лечение антикоагулянтами.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>заимодействие с другими лекарственными средствами и другие виды взаимодействий.</b><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Поскольку </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>системн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>являются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дитивн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ми, буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ует</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с осторожностью применять </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нтам, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>которые получают другие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тные </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетики </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>или </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>которые по структуре подобны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тным </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ам </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>ам</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного тип</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, например </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>определенные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>антиаритм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, так</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif"' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>как </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дока</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> мексилетин. Специфич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские исследования </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вза</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имодействий </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ду</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> буп</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ном </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> антиаритм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ескими </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенными средствами </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>клас</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>са</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> ІІІ (напри</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>мер</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>одароном) не проводилис</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>однако в</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> таком </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>случае </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рекоменду</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>тся</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> придерживаться </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>сторожности </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>(</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л «Особ</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>»).</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>О</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>стра</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>я</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> системна</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>я</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> токсичн</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>о</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>сть</i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Системн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> гл</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>образом касаются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ЦНС </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дечно</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>-сосудистой систем</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Появление таких реакций </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>обусловлено </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ысокой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией местных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в в кров</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>которая </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>т</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ь</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>обусловлена </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>(</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>случайным</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>) внутр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>исосудистым </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ием </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>препарата, передоз</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ировкой или исключительно быстрой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>абсорбц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией из </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>сильно васкуляриз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ированных участков </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>(</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л «Особ</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>енности применения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>»). Реакции </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>со стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ЦНС сходны для вс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>с</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в ам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дного тип</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, в то</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> время как </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>со</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif"' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дца в</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> б</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льш</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ей</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>степени </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>висят от типа </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>как</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>оличественно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, так </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>качественно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Токсич</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>еское </i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>вли</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>яние</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> на Ц</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>НС </i><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>представляет </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>собо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> по</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>тапну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> реакц</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ю </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>симптомами и </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>приз</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>наками, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>которые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>провож</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>даются возрастанием </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> тяж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ести</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>начала наблюдаются </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>так</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> симптом</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ка</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>к легк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>е </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>головокружение</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>колоротова</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> парестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я, он</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> яз</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ка, г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>перакуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я, зв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>н в у</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>шах и нарушение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ения</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>. Дизартрия, риг</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сть м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ышц и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>тремор являются б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>олее с</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>ер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ьезными </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>симптомами </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ут пред</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>шествовать началу </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>генерал</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зован</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ных </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>судо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>рог</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>. Э</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ти признаки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>не сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ует</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>шибочно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>при</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>нимать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>за невротич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еское </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>повед</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. П</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>этого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>наблюдаться потеря сознания и большой э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>лептич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еский припадок</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>который </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>же</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>т </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>длиться от н</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>е</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х секунд до не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>минут</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. о время судорог из-за повышенной м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ышечной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>активн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>быстро </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звиваются кис</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>лородная </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>недостат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очность и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>перкапния </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>вместе с на</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рушением д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>хан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>возможным ухудшением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>функц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ха</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тельных путей</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>. тяжелых случаях может развиться апноэ. Развитие ацидоза, гиперкалиемии и дефицита кислорода</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> увеличивает и удлиняет </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>с</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ыздоровление происходит </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>следствие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>перер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>аспределения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика за </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>границами ЦНС и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>дальнейшего </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>метаболизм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кскрец</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ыздоровление м</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>оже</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ыть быстрым</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, за </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>исключением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>случаев</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гда </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ыли </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>большие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ичества </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>екарственного средства</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> тяж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>елых случаях </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>наблюдаться </span><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>токсич</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>еское </i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>вли</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>яние</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> на сер</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>дечно</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>-с</i><i style='mso-bidi-font-style: normal' style='mso-bidi-font-style: normal'>осудистую </i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>систему</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>.</i><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Как правило, </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ескому </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вли</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>янию </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> на сер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>дечно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>осудистую </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>систему пред</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>шествуют признаки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ия </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еского </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вли</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>яния </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ЦНС</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Продромальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>симптом</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>со стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ЦНС мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут не в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>озникнуть </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>у пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нт</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в, находя</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>щихся </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ействием </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сильн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х седативн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенных средств или получают </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат для общей анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. результате высоких системных концентраций мес</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ся артер</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>альна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я, брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я, аритмия </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>даже остановка с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ердца, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>но </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>в р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>их случаях остановка </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>наблюдалась </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>без продромальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>эф</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>со стороны </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ЦНС.</span></p> <p><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>Л</i><i style='mso-bidi-font-style: normal' style='mso-bidi-font-style: normal'>ечение </i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>остро</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>й</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'> токсичност</i><i style='mso-bidi-font-style:normal' style='mso-bidi-font-style:normal'>и</i></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>При в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>оз</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>никн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>овении признаков </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>остро</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> системно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>применение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ует</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>медленно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>екратить</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Лечение пациента с </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>признаками </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>системно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>должно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>направлено </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>быстрое прекращение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>судо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>рог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>обеспечение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>адекватно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> вентиляц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>предоставлением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кис</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>лорода</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>при необходимости</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, для </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>облегчения или </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>контрол</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> вентиляц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> (респ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>) лег</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ких</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>П</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> того, </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ка</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к судо</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>роги </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ста</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>новятся </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>контрол</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ируемыми и обеспечивается </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>адекватна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> вентиляц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я лег</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ких</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>обычно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>потреб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ности в на</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>значен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>другого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ечения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> случае угнетения сердечно-сосудистой функции (артериальная гипотензия, брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я) сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ует</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ассмотреть вопрос </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о назначении </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>соответствующего </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ечения с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> внутр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ивенным </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ием жидкости</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, вазопрес</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>орного </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>средства</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, инотроп</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>/</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>или</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> л</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пидно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>мульс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. При л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ечении </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>симптом</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> у д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>тей сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>применять </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>соответствующие их </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>озрасту и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мас</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>се</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> т</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ла.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> случае остановки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кровооб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ращения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>медленно начать мероприятия по</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ю сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>дечно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-лег</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очной </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. Под</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>держание </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>леж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ащего уровня </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>оксигенации, вентиляц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> лег</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ких и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кровооб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ращения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, а такж</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ечение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ацидоз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ют жи</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>зненно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>важ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ное </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>значен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Остановка </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дца</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, в</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ызванная применением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, може</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ыть у</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ойчивой к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> электрич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еской </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>деф</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>брил</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>яц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>поэ</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>тому </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>на протяжении длительного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>од</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>времени </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>необх</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имо </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>активно продо</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>лжать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионных мероприятий</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Проявления обширной или полной спинномозговой блокады, приводящие к развитию дыхательного паралича и артериальной гипотензии во время эпидурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> л</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ечить путем о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>бе</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>печен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>оддержания свободной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>прох</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имости </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ха</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тельных путей</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, а для </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>облегчения или </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>контрол</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я в</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>ентиляц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> лег</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ких </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>предоставить </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кис</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>лород</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><b style='mso-bidi-font-weight:normal' style='mso-bidi-font-weight:normal'>Особенности применения.</b><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'></span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Существуют сообщения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>случаях остановки </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>во время применения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> для </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>или</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> периферич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еских н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> некоторых случаях </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ла </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>осложненной и требовалось </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие длительных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионных мероприятий </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>до дос</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тижения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>позитивно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>го</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> ответа со стороны пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нта. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> некоторых случаях </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>оказалась </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>воз</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>можной, не</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>смотря </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на очевидно адекватну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дготовку </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> на</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>леж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ащую </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>терап</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ю.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Как и все </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тные </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетики, буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>в</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>случаях</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гда применение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>целью </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведения м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>с</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>тной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> приводит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> к образованию </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>соких концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й препарата в кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, може</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>вызвать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>остр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х токсич</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>еских эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> со стороны ц</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ентрально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> нерв</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ной и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>дечно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>осудистой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>систем. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Это в частности касается случаев</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>которые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звиваются п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>сле </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>случайного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>исосудистого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>или</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в сильно васкуляриз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ированные участки</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Случаи желудочковой аритмии, фибрилляции </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>желудочков</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>внезапной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дечно</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>-с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>осудистой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>недостат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очности и летальные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>лучаи </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ли заре</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>гистрированы </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вяз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и с</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> в</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сокими системными концентрациями буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Соответствующее </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>об</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>орудование должно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ыть всегда </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доступн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>при </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пров</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ении </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тной или общей </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>Ответственный врач должен принять </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>необх</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имые меры предосторожности</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>чтобы избежать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>исосудистого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> (</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>см</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>. р</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л «Спос</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>б </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>применения и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>»). Пр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ежде чем начать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие какой</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>либо </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>блокадно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, необх</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имо обеспечить </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>доступ для внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ивенного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенных средств с целью </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я реан</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионных мероприятий</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>рачи должны получить соответствующий и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>достат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очный уровень </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дготовки для проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я процедур</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>должны быть </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>озна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>комлены с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>агностико</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>л</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ечением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>поб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>чных </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>эф</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в, системно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>или других осложнений </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>(</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>см</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зд</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> «Передоз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ировка</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>» </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> «Поб</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>чн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>»).</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Блокад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>больших </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>периферич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еских </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>же</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>т треб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ват</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь применения больших </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>об</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ъемов </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика на </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>сильно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>васкуляриз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ированных участках</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, часто </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>вблизи больших сосудов</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>де </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>существует </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>овышенный риск </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>исосудистого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>/</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>или</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> системно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> абсорбц</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Это</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>образованию </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>соких концентраций препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в плазм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Передоз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ировка или</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>случайное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ивенное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие п</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>репарата може</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ию </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еских </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Из-за медленного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>накоп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ления </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дрохлорид</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> введен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>повторн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х доз може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> привести к знач</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ительному увеличению уровней </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> в кров</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ж</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>дой п</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>овторно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> дозо</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Переносимость препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>зм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>яется одновременно с состоянием </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нта.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Хотя регионарная анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я часто </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>является </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>оптимальн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м методом проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>некоторые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нт</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> для того, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>чтобы с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>низит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ри</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ск </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>р</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ия </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>не</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>желательных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>поб</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>чн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>х </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>эф</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в, требуют</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ого внимания</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>:</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нтам пожилого возраста и </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>п</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нтам </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> ослаблен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ны</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>м </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>общим состоянием </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>здоровья необх</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имо уменьшить </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дозу препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>опоставимо с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>х ф</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еским </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>остоянием</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пациент</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> част</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>ичной или </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>по</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>но</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокадо</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>д</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ц</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> – </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>из-за того</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>что</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тные </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетики мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> угнетать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пров</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>одимость </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>окарда.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нт</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> прогрес</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>сирующим </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>болеванием </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>печ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ени или </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>тяж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>елой почечной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дисфункц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нт</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>на</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>з</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дних </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>стад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ях </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>беременности</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Пациенты, которые принимают антиаритмич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские средства </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ІІІ клас</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>са</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> (напри</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>мер</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ам</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>одарон), </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>должны находиться </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тщательным </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>блюдением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>персонал</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а, также должен </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проводит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ся </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> Э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>КГ-</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>контроль</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>п</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>оск</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>у</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> кард</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>олог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ут б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ыть </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>д</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>итивн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ми.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Пациенты с аллергич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еской </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией н</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>а м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тные </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетики </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ф</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рного тип</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> (прока</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н, тетрака</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н, бензока</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н и т.д.) не продемонстр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ировали </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пере</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>крестной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>чу</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>вствительности к </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ам </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>ам</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного тип</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, таки</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ка</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>к буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Некоторые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>процедур</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>связанные с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>с</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>тной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>, мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ут</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>приводит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь к развитию </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ьезных н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>е</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>желательных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й, неза</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>висимо от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>типа </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>примененного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Местные анестетики должны применяться с осторожностью для эпидуральной анестезии у пациентов с </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>нарушенной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>дечно</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>-с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>осудистой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>функцией, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>п</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>оск</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>у</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> так</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>нт</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имеют </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>мен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ше </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>возможностей </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>компенс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ировать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>функц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ональн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые изменения</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>связанные с удлинением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>атр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>овентрикулярно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> пров</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>имости</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, вызван</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ной</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ействием этих</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> л</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенных средств</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Физ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>олог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>развивающиеся в</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> результат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я центрально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> неврально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>олее </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ражен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> при наличии артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>. о время проведения эп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> у пац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ие</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>нт</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> г</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>поволем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>по </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>какой</span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>-</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>либо </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>причин</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> може</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> разви</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ться внезапная и тяжелая </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>альна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я. Поэтому у пациент</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>с</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> нел</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>еченной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>поволем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ией или </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>знач</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ительным на</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>рушением венозного </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>оттока следует избегать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>проведен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>э</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>п</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>или применять ее с </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>сторожностью</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>очень </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дких случаях ретробульбарн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые инъе</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> мо</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>гут </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дос</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тигать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>черепного субарахно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дального простр</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>анства и вызывать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>появ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ление</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif"' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>временной </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пот</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, сер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>дечно</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-сосудистой недостат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>очности</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, апноэ </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> судо</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>рог.</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'></span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Ретро- и околобульбарн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые инъе</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> м</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>естных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гут </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>оставлять определенный риск </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>для развит</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ия </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>йко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> дисфункции глазных м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ышц</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>. Основн</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ми причинами </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>являются т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>равматиче</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ское поражение </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>/</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>или</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>естные </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>токсич</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фект</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> введен</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>н</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ого м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>с</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>тного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетика на м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ышцы и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. Тяж</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>есть </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>таких ткан</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>евых </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>й за</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>висит от </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> травм</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, концентрац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> м</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif"' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>длительности </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>оздействия </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика на ткани. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>По этой</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> причин</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ка</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>к </span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>и в случае со всеми </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тными </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетиками, сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ует</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>применять самую </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ни</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>зкую эф</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>фективну</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ю</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> концентрацию </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> дозу м</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тного </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>анестетика.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- С</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>осудосуживающие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>карс</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>твенные средства </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>г</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ут</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> у</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сил</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ват</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>реакц</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> ткан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ей, поэтому должны применяться </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льк</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> то</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>г</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, ко</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>гда это </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>показано.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Случайное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутриартериальное введени</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> низких доз мес</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>тных </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в в </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>участок </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>голов</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> ш</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>и, включа</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>я р</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>етробульбарн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ые</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>, стоматолог</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>еские </span><span lang='UK' style='font-size: 12.0pt;font-family:"Times New Roman","serif"'>блокад</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> блокаду з</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>вездчатого </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>узла, мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>же</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'> </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>к</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> р</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ию </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>системно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> токсичност</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- Парацерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кальна</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>я</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокада може</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>т</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>оказывать </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>б</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льш</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ее</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> негативн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ое </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>в</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>лияние </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на пл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>д, </span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>чем другие в</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ид</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ы</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>применяемой </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в акушерств</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокадно</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> анестез</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>Из-за </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>системн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ой т</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>оксичн</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ст</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>следует быть </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>особ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>енно </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>о</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>сторожными </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>при </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>применении </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>буп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>вака</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>н</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> для парацерв</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> блокад</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>ы</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>- </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Зафиксированы </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>случа</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>хондролиза у пациентов, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>которые в </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>слеоперац</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ионный </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>пер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>од </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>получали </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>исуставные длительные и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нфуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> м</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тных </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетик</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'> </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>б</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>льшинстве </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>случаев сообщалось </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>а</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>звит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>хондролиз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>с вовлечением </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>плечевого су</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>става</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>Из-за </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>на</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>личия определенного </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>к</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>о</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>л</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ичества </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сп</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>особствующих </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>причин и </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>противоречивых </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нау</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>чных </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>дан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ны</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>х о механ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>зм</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ействия </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>причинно-сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ственная связь не была у</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>становлен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а. Длительная </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>исуставная и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>нфуз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>я не </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>является утвержденным </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>показан</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ием </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>для </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>применения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>а</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>.</span></p> <p><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>Проведение эпидурально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>анестез</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>каким</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>-</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>либо </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>м</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>тным </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>анестетиком може</span><span style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt;font-family: "Times New Roman","serif";mso-ansi-language:RU'>т</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> привести </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>азвитию </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> брадикард</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>, появ</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ление которых </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>сл</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> пред</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>видеть и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> проводит</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь соответствующие предупреждающие мероприятия</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>которые </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>мо</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>гут </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>включат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ь </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>и п</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>редварительное </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>введен</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ие </span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'>в систему кровооб</span><span style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size: 12.0pt;font-family:"Times New Roman","serif";mso-ansi-language:RU'>ращения </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кристал</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного или кол</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>л</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>о</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>дного р</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>аствора</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>. </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>случае развития </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>артер</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>и</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ально</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>й</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>потенз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> сл</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>д</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ует</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'> внутр</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ивенно </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>ввести с</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>осудосуживающий </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>препарат, так</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>ой как э</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>федрин</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>,</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>в </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>доз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> 10-15 мг. Тяжелая артериальная гипотензия может в</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>озникнуть </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>в результат</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>е</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'> г</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU' style='font-size:12.0pt;font-family:"Times New Roman","serif"; mso-ansi-language:RU'>и</span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>поволем</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='UK' style='font-size:12.0pt;font-family: "Times New Roman","serif"'> в</span><span style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU' style='font-size:12.0pt; font-family:"Times New Roman","serif";mso-ansi-language:RU'>следствие </span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>кровотеч</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ения или обезвоживания</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>, </span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>или </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>аорто-по</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>лой </span><span lang='UK' style='font-size:12.0pt; font-family:"Times New Roman","serif"'>ок</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>к</span><span lang='UK' style='font-size:12.0pt;font-family:"Times New Roman","serif"'>люз</span><span style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU' style='font-size:12.0pt;font-family:"Times New Roman","serif";mso-ansi-language: RU'>ии</span><span lang='